Title : Pharmacological properties and water and olive oil soluble products of fullerene C60
Abstract:
Fullerene (C60) is a spherical carbon molecule which has a unique cage structure. The bio-activity of C60 derivatives demonstrates their potential for medical applications. C60 is rapidly absorbed by tissues and excreted via the urinary tract and enterons, showing low toxicity in in vitro and in vivo studies. Water-soluble C60 derivatives from chemical modification greatly increase biological activity. A great deal of information has accumulated on the beneficial effects of fullerenes and their water-soluble derivatives. neuroprotection, radio protection, antiproliferative, antitumor, anti-inflammatory activities. Still studies are focused on pharmacological, cosmetic and food supplement/food enrichment uses of water-soluble and oil-soluble forms of C60. This study is aimed to present pharmacological properties of fullerene C60, current studies with future expectations and provide information about the products produced by dissolving C60 in water and olive oil. It’s pharmacological properties such as anti-cancer and chemoprotective capabilities appear to be complex and situation-dependent. For this reason, much more research is necessary before C60 fullerene can be considered a safe and effective treatments. More data is required to understanding mechanism of action in the systems of mammals.
It is known that in some countries, especially European countries and the United States, C60 is marketed dissolved forms in water and olive oil. In addition, it is seen that the online sales volumes of this sector are increasing every year. There are studies on its protective effects against diseases, especially its immune-boosting effect. However, the majority of these studies were conducted on animals or in vitro environments. Although many studies mention its potentially positive effects on health, it has been reported that more detailed and comprehensive research can be obtained in the future. For instance in a molecular and cytogenetic research results reported that C60 and virgin olive oil can exhibit anti-genotoxic agents against cadmium chloride (cadmium is known as one of the important environmental pollutant) induced genotoxicity in rats. Along with these positive results, it was reported in the same study that the most suitable conditions for these positive potential effects should be investigated and that more beneficial results could be achieved through further research. There are studies on the positive effects that can occur when C60 is used with medicinal plants or with olive oil. Perhaps in future studies, the effects that may occur when C60 is used together with prebiotics or probiotics may be the subject of new research and interesting results may be obtained.
Audience Take Away:
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By learning the properties of the products produced by dissolving C60 in water and olive oil, trade and production of these products or research in this field can be carried out.
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C60's forms in water and olive oil are still a new product. People who will do business or R&D in this field early may be more successful. Because the number of studies and production in this field is quite less compared to traditional products.
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C60 and C60 products are newly recognized. The number of studies conducted in this field is small. So it is an untouched subject. New research and projects can be developed by adding to existing research or only on C60.
